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| 1949 SCHEDULEOverall 10-0Home 4-0Away 4-0Neutral 2-0 |
| Date | Opponent / Event | Location | Time / Result | Media | |
| Sat., Sep. 24 | vs. Indiana |
Notre Dame, Ind. | W, 49-6 | More | |
| Sat., Oct. 1 | at Washington |
Seattle, Wash. | W, 27-7 | More | |
| Sat., Oct. 8 | at Purdue |
West Lafayette, Ind. | W, 35-12 | More | |
| Sat., Oct. 15 | vs. Tulane |
Notre Dame, Ind. | W, 46-7 | More | |
| Sat., Oct. 29 | vs. Navy |
Baltimore, Md. | W, 40-0 | More | |
| Sat., Nov. 5 | at Michigan State |
East Lansing, Mich. | W, 34-21 | More | |
| Sat., Nov. 12 | vs. North Carolina |
Bronx, N.Y. | W, 42-6 | More | |
| Sat., Nov. 19 | vs. Iowa |
Notre Dame, Ind. | W, 28-7 | More | |
| Sat., Nov. 26 | vs. USC |
Notre Dame, Ind. | W, 32-0 | More | |
| Sat., Dec. 3 | at SMU |
Dallas, Texas | W, 27-20 | More | |
Schedule Key Home Event Away Event