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| 1966 SCHEDULEOverall 9-0-1Home 5-0Away 3-0-1Neutral 1-0 |
| Date | Opponent / Event | Location | Time / Result | Media | |
| Sat., Sep. 24 | vs. Purdue |
Notre Dame, Ind. | W, 26-14 | TV: ABC | More |
| Sat., Oct. 1 | at Northwestern |
Evanston, Ill. | W, 35-7 | More | |
| Sat., Oct. 8 | vs. Army |
Notre Dame, Ind. | W, 35-0 | More | |
| Sat., Oct. 15 | vs. North Carolina |
Notre Dame, Ind. | W, 32-0 | More | |
| Sat., Oct. 22 | at Oklahoma |
Norman, Okla. | W, 38-0 | More | |
| Sat., Oct. 29 | vs. Navy |
Philadelphia, Pa. | W, 31-7 | More | |
| Sat., Nov. 5 | vs. Pittsburgh |
Notre Dame, Ind. | W, 40-0 | More | |
| Sat., Nov. 12 | vs. Duke |
Notre Dame, Ind. | W, 64-0 | More | |
| Sat., Nov. 19 | at Michigan State |
East Lansing, Mich. | T, 10-10 | Recap/Stats TV: ABC (Regional) | More |
| Sat., Nov. 26 | at USC |
Los Angeles, Calif. | W, 51-0 | More | |
Schedule Key Home Event Away Event